Endocrinology: A Sneak Peek

A healthy human body is an example of a perfect creation made by our God Almighty. The way your heart pumps involuntarily, you breathing freely, your reflexes and a lot more!  Being a human, we are capable of having deep thoughts, emotions and decisions. We always think that the heart controls our emotions because when we are feeling something like when we are in-love, we can feel our chest like it is burning from the inside. An unexplainable feeling. What most people aren’t aware of is that our brain controls everything. Hormones on the other hand could somehow control a variety of human functions, including metabolism, developmental growth, tissue function and mood.  Hormones serve as chemical messengers inside our body. Each of the hormones is being formed by a specific tissue of origin which will then be freed in the bloodstream and carried to the site of action. Usually, hormones act at a specific site or sites (target cells) to stimulate certain characteristic biochemical changes. The collection of hormones, carrier proteins and other components of these processes is called the endocrine system. Hormones are indeed very important in our body. Underproduction and overproduction of these could give clinical significance like Diabetes which is one of the most common diseases here in the Philippines. Over 6,000 endocrine disorders have been discovered but there are still a lot more that are still hiding.


Types of hormones


1. Corticotropin releasing factor (CRF)
2. Gonadotropin releasing hormone (GRH)
3. Growth hormone inhibitory hormone
4., Thyroid releasing hormone
5. Vasopressin / Antidiuretic hormone (ADH)
6. Oxytocin
7. Adrenaline
8. Noradrenaline
9. Insulin

One of the disorders that caught my attention is the Male Pseudohermaphroditism or MPH. Testosterone is a male hormone. It doesn’t work unless it binds to certain proteins in our body cells. Once there is a dysfunction in these proteins the cells will not work with the male hormone. We all started as girls. Our genes which came from both our mother and father will differentiate our sexes later on. Ovaries develop into testes and drop then a fetus with an XY chromosome (boy) develops into something out of the ordinary. The testes never descended. From the outside, people with this disorder will develop as a female which looks completely normal. 

http://accessmedicine.net/search/searchAMResultImg.aspx?rootterm=testicular+feminization&rootID=36038&searchType=1
An infant with MPH


There is a number of hormones in our body. Because of these, they have been classified by their arrangement and their tissue of origin. All of which have their own importance and functions. There is still a great number of things involving our human body that wait for someone who will discover them. We still have a long way to go.



References:

Calbreath, Donald F. Clinical Chemistry A Fundamental Textbook
http://emedicine.medscape.com/endocrinology